Real-world evidence and health systems
Population-level methods for therapy funding, costing, utilization, and outcomes in public payer environments.
PhD Epidemiologist | Senior Quantitative Methodologist
Decision-grade epidemiology for health systems, oncology, and population health.
Akinkunle (Akin) Oye-Somefun translates clinical questions into rigorous real-world evidence, reproducible statistical pipelines, and publishable research outputs for health-system and academic decision makers.
Research identity
Methods that stand up to clinical, payer, and peer-review scrutiny.
Akin works across observational study design, systematic reviews, causal inference, survival analysis, microcosting, survey-weighted analysis, and validated SAS/R/Python workflows.
Research themes
Focused evidence programs
Movement behaviours and brain health
Evidence synthesis on physical activity, sedentary time, sleep, and dementia risk across cohort studies.
Oncology outcomes and supportive care
Observational study design and statistical pipelines for gynecologic oncology and supportive care delivery.
NHANES and chronic disease epidemiology
Complex survey analysis linking biomarkers, metabolic syndrome, viral exposures, and mortality outcomes.
Thesis prototype
Movement Behaviours and Dementia Evidence Explorer
An interactive research prototype based on the published meta-analysis of physical activity, sedentary behaviour, sleep duration, and incident dementia among community-dwelling adults aged 35 years and older.
Regular physical activity
Combined relative-risk pattern
0.95 RR-5% vs reference patternNear reference pattern95% CI: 0.68 to 0.82
95% CI: 1.17 to 1.39
95% CI: 1.09 to 1.28
95% CI: 1.15 to 1.43
Research prototype only. This educational visualization combines pooled relative-risk estimates and is not a clinical risk calculator or medical advice.
Missing
Thesis PDF
Reserved for the full thesis manuscript, abstract, citation, defense date, supervisor details, and download link.
Missing
Dataset
Reserved for dataset metadata, study population, variable dictionary, access notes, and reproducibility constraints.
Supplementary evidence
Available materials now mapped into the prototype
The available dementia and treadmill supplementary files have been converted into public-facing summaries. Raw Word/PDF source files are not hosted in this version.
Available
Dementia SRMA supplement
Movement behaviours and incident dementia
Supplementary materials now support the prototype with search strategy details, study-characteristic tables, funnel-plot inventories, and risk-of-bias assessments.
49 physical activity studies; pooled RR 0.75, 95% CI 0.68 to 0.82
17 sleep-duration studies; short sleep RR 1.18 and long sleep RR 1.28
3 sedentary-behaviour studies; prolonged sitting RR 1.27, 95% CI 1.17 to 1.39
Tables and methods
- S1 MEDLINE search strategy
- S2 physical activity study characteristics
- S3 sleep duration study characteristics
- S4 sedentary behaviour study characteristics
- S9-S11 risk-of-bias assessments
Figure inventory
- S5 funnel plot: physical activity
- S6 funnel plot: short sleep
- S7 funnel plot: long sleep
- S8 funnel plot: sedentary behaviour
Available
Treadmill desk SRMA supplement
Treadmill desks, energy expenditure, sitting time, and cardiometabolic health
Supplementary files now provide table-level evidence for laboratory and workplace settings, plus forest-plot and funnel-plot figure inventories.
Laboratory setting: energy expenditure +105.23 kcal/hour, 95% CI 90.41 to 120.04
Laboratory setting: VO2 +5.0 mL/kg/min, 95% CI 3.35 to 6.64
Workplace setting: full-day sitting time -1.73 minutes/hour, 95% CI -3.30 to -0.17
Workplace setting: working-hours sitting time -3.58 minutes/hour, 95% CI -7.17 to 0.02
Tables and methods
- Table 1 laboratory study characteristics
- Table 2 workplace study characteristics
- Table 3 laboratory meta-analysis results
- Table 4 workplace meta-analysis results
- Electronic search strategy
Figure inventory
- Figure 1 PRISMA flow diagram
- Figure 2 laboratory forest plots
- Figure 3 workplace forest plots
- Figure 4 laboratory funnel plots
- Figure 5 workplace funnel plots
Publications
Selected peer-reviewed work
2026 | Lead author
The relationships between physical activity, sedentary behaviour, sleep, and dementia: A systematic review and meta-analysis of cohort studies
PLOS ONE
2025 | Co-author and statistician
Predictors of supportive care in young adults diagnosed with a gynaecologic malignancy
Journal of Obstetrics and Gynaecology Canada
2024 | Co-author
Association between human papillomaviruses, metabolic syndrome, and all-cause death; analysis of the U.S. NHANES 2003-2004 to 2015-2016
PLOS ONE
2021 | Lead author
A systematic review and meta-analysis of the effect of treadmill desks on energy expenditure, sitting time and cardiometabolic health in adults
BMC Public Health
2021 | Lead author
Associations between elevated kidney and liver biomarker ratios, metabolic syndrome, and all-cause and coronary heart disease mortality
BMC Cardiovascular Disorders
2021 | Lead author
Trends in serum AST-to-ALT ratio among U.S. adults
Metabolic Syndrome and Related Disorders
CV
Experience and training
Senior Methodologist, Sector Capacity and Performance
Ontario Health (Cancer Care Ontario)
Led real-world evidence, microcosting, and administrative data methods for high-cost therapies and provincial funding models.
Biostatistician, Clinical Research in Brain Health
Baycrest Hospital, Rotman Research Institute
Directed statistical methodology for Ministry-funded initiatives, randomized trials, program evaluations, and digital health interventions.
Senior Statistician, Gynecologic Oncology
Sunnybrook Research Institute
Provides methodological and biostatistical oversight for observational oncology studies, protocols, SAPs, and manuscripts.
Research Consultant, Epidemiology and Biostatistics
York University, Faculty of Health
Designed epidemiologic analyses, systematic reviews, meta-analyses, and NHANES pipelines for population health research.
Education
PhD, Epidemiology, York University, 2018 - 2024
MSc, Epidemiology, York University, 2016 - 2018
BA, Specialized Honours, Kinesiology and Health Science, York University, 2011 - 2015
Media